NCLEX Addison vs Cushing cheat sheet

A cheat sheet comparing Addison's disease and Cushing's syndrome for NCLEX exam preparation, covering symptoms, lab values, nursing interventions, and key differences.

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Addison's Disease primary cause?

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Autoimmune destruction of adrenal glands.

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Quiz(48 questions)

Question 1 of 48

1. What is the primary cause of Cushing's Syndrome?

Terms in this Study Set(48)

Addison's Disease Overview(16)

Addison's Disease primary cause?

Autoimmune destruction of adrenal glands.

Key hormone deficiencies in Addison's?

Cortisol and aldosterone deficiencies.

Common symptoms of Addison's Disease?

Fatigue, weight loss, low blood pressure, hyperpigmentation.

True or False: Addison's can lead to hyperglycemia.

False. It typically causes hypoglycemia.

Nursing priority in Addisonian crisis?

Administer IV hydrocortisone immediately.

Fill in the blank: Addison's may cause ___________ sodium levels.

decreased

Clinical sign of hyperpigmentation?

Bronze skin, especially in sun-exposed areas.

What lab values indicate Addison's?

Low cortisol, low aldosterone, high ACTH.

Addison's Disease can lead to?

Adrenal crisis due to stress or infection.

Nursing action for low blood pressure in Addison's?

Monitor vital signs; administer IV fluids.

Common electrolyte imbalance in Addison's?

Hyponatremia (low sodium) and hyperkalemia (high potassium).

What is the significance of ACTH stimulation test?

Differentiates primary from secondary adrenal insufficiency.

True or False: Stress increases cortisol production in Addison's.

False. Patients cannot produce adequate cortisol.

Symptoms of Addison's Disease include?

Nausea, vomiting, abdominal pain, low energy.

Long-term treatment for Addison's includes?

Lifelong glucocorticoid and mineralocorticoid replacement.

What should patients carry for Addison's?

Emergency hydrocortisone injection kit.

Cushing's Syndrome Overview(16)

Cushing's Syndrome Overview

Endocrine disorder caused by excess cortisol.

Key Features of Cushing's Syndrome

- Moon face - Buffalo hump - Central obesity - Purple striae

Main Symptoms of Cushing's Syndrome?

- Hypertension - Hyperglycemia - Osteoporosis - Muscle weakness

True or False: Cushing's causes weight loss.

False. Cushing's typically causes weight gain due to fat redistribution.

What lab value indicates Cushing's?

Elevated cortisol levels in blood and urine.

Nursing Action for Cushing's Syndrome

Monitor vital signs and glucose levels.

Cause of Cushing's Syndrome?

Excessive exposure to cortisol from adrenal tumors or prolonged corticosteroid use.

Fill in the blank: Cushing's Syndrome patients often have ___ skin.

thin, fragile skin.

Cushing's Syndrome vs Addison's Disease

Cushing's: high cortisol, Addison's: low cortisol.

Common Psychological Symptoms

- Mood swings - Depression - Anxiety

Assessment for Cushing's Syndrome

Look for signs of fluid retention and hypertension.

How to diagnose Cushing's Syndrome?

24-hour urinary free cortisol test, low-dose dexamethasone suppression test.

Treatment Options for Cushing's

- Surgery - Radiation - Medications (e.g., ketoconazole)

What is the primary concern for Cushing's patients?

Risk of cardiovascular disease and infections.

Nursing Education for Cushing's patients

Teach about medication adherence and lifestyle changes.

Primary Lab Test for Diagnosis

Late-night salivary cortisol test.

Comparative Analysis(16)

Addison's disease symptoms

Fatigue, weight loss, low blood pressure, hyperpigmentation.

Cushing's syndrome symptoms

Weight gain, moon face, hypertension, easy bruising.

Primary hormone deficiency in Addison's

Cortisol and aldosterone deficiency.

Primary hormone excess in Cushing's

Excess cortisol production.

Addison's disease skin changes

Hyperpigmentation, particularly in sun-exposed areas.

Cushing's syndrome skin changes

Thin skin, purple striae, easy bruising.

Addison's vs. Cushing's: Blood glucose levels

Addison's: low; Cushing's: high.

True or False: Addison's requires glucocorticoid replacement

True - to manage hormone deficiency.

True or False: Cushing's causes weight loss

False - Cushing's causes weight gain.

Addison's crisis triggers

Stress, illness, trauma, non-adherence to therapy.

Normal cortisol levels (morning)

Approximately 10-20 mcg/dL.

Diagnosis method for Addison's disease

ACTH stimulation test; low response indicates Addison's.

Diagnosis method for Cushing's syndrome

24-hour urine free cortisol test; elevated levels indicate Cushing's.

Addison's vs. Cushing's: Electrolyte imbalances

Addison's: hyponatremia, hyperkalemia; Cushing's: hypokalemia.

Cushing's syndrome treatment

Surgery, medications, or radiation therapy to reduce cortisol.

Addison's disease treatment

Glucocorticoids and mineralocorticoids replacement therapy.

Questions in this Study Set(48)

1. What is the primary cause of Cushing's Syndrome?

A.Excess cortisol production
B.Decreased cortisol production
C.Insulin resistance
D.Thyroid hormone excess

2. What is the primary cause of Addison's Disease?

A.Autoimmune destruction of adrenal glands
B.Tumor of the adrenal cortex
C.Chronic infection
D.Genetic mutation

3. Which symptom is commonly associated with Addison's disease?

A.Fatigue
B.Weight gain
C.Moon face
D.Hypertension

4. Which of the following is a characteristic physical feature of Cushing's Syndrome?

A.Moon face
B.Pallor
C.Goiter
D.Jaundice

5. Which hormones are deficient in Addison's Disease?

A.Cortisol and aldosterone
B.Insulin and glucagon
C.Thyroid hormones
D.Estrogen and testosterone

6. What is a hallmark symptom of Cushing's syndrome?

A.Hyperpigmentation
B.Hypotension
C.Moon face
D.Weight loss

7. Which symptom is most commonly associated with Cushing's Syndrome?

A.Hyperglycemia
B.Bradycardia
C.Weight loss
D.Hyponatremia

8. A patient with Addison's might present with which of the following symptoms?

A.Increased appetite
B.Weight gain
C.Low blood pressure
D.High energy levels

9. Which hormone deficiency is primarily found in Addison's disease?

A.Cortisol and aldosterone
B.Estrogen and progesterone
C.Insulin and glucagon
D.Thyroid hormones

10. True or False: Patients with Cushing's Syndrome often experience muscle weakness.

A.True
B.False
C.Not enough information
D.Only in advanced cases

11. True or False: Addison's Disease can lead to hyperglycemia.

A.True
B.False
C.Depends on treatment
D.Only in emergencies

12. How do blood glucose levels compare between Addison's disease and Cushing's syndrome?

A.Both are high
B.Both are low
C.Addison's low; Cushing's high
D.Addison's high; Cushing's low

13. What lab test is commonly used to diagnose Cushing's Syndrome?

A.24-hour urinary free cortisol test
B.Complete blood count
C.TSH test
D.Electrolyte panel

14. What is the priority nursing intervention during an Addisonian crisis?

A.Administer glucose
B.Provide emotional support
C.Administer IV hydrocortisone
D.Increase fluid intake

15. Which of the following is NOT a treatment option for Cushing's syndrome?

A.Surgery
B.Glucocorticoid replacement
C.Medications
D.Radiation therapy

16. Which is NOT a common psychological symptom of Cushing's Syndrome?

A.Mood swings
B.Depression
C.Anxiety
D.Euphoria

17. Fill in the blank: Addison's Disease may cause __________ sodium levels.

A.Increased
B.Normal
C.Decreased
D.Fluctuating

18. What is a common skin change seen in Addison's disease?

A.Thin skin
B.Purple striae
C.Hyperpigmentation
D.Easy bruising

19. What is a possible nursing action for a patient with Cushing's Syndrome?

A.Monitor vital signs
B.Encourage high-salt diet
C.Limit fluid intake
D.Administer insulin

20. What clinical sign is indicative of hyperpigmentation in Addison's Disease?

A.Pale skin
B.Yellowing of the eyes
C.Bronze skin
D.Rash

21. What is the primary diagnostic test used for Cushing's syndrome?

A.ACTH stimulation test
B.24-hour urine free cortisol test
C.Serum aldosterone test
D.Blood glucose test

22. Fill in the blank: Patients with Cushing's Syndrome may have ___ skin.

A.Thin and fragile
B.Thick and oily
C.Dry and flaky
D.Rough and calloused

23. Which lab values are indicative of Addison's Disease?

A.High cortisol, low aldosterone
B.Low cortisol, low aldosterone, high ACTH
C.Normal cortisol, normal aldosterone
D.High ACTH, normal cortisol

24. Which electrolyte imbalance is commonly found in Addison's disease?

A.Hypokalemia
B.Hypernatremia
C.Hyponatremia
D.Hypocalcemia

25. How does Cushing's Syndrome typically affect weight?

A.Weight gain
B.Weight loss
C.No change
D.Increased muscle mass

26. What potential complication can arise from Addison's Disease?

A.Hypertension
B.Adrenal crisis
C.Diabetes
D.Hyperthyroidism

27. True or False: Cushing's syndrome can lead to muscle wasting.

A.True
B.False
C.Depends on the severity
D.Rarely

28. Which condition is a risk factor for developing Cushing's Syndrome?

A.Prolonged corticosteroid use
B.Low blood sugar
C.High thyroid hormone levels
D.Chronic dehydration

29. What nursing action is appropriate for a patient with hypotension due to Addison's?

A.Monitor vital signs
B.Administer antihypertensives
C.Encourage caffeine intake
D.Limit fluid intake

30. Which of the following could trigger an Addison's crisis?

A.Routine exercise
B.Stress
C.Balanced diet
D.Medication adherence

31. What is the best treatment option for a patient with Cushing's Syndrome caused by an adrenal tumor?

A.Surgery
B.Dietary changes
C.Physical therapy
D.Increased fluid intake

32. Which electrolyte imbalance is commonly associated with Addison's Disease?

A.Hypernatremia
B.Hyponatremia and hyperkalemia
C.Hypokalemia
D.Normal electrolyte levels

33. What is the normal range for morning cortisol levels?

A.5-10 mcg/dL
B.10-20 mcg/dL
C.20-30 mcg/dL
D.30-40 mcg/dL

34. Which statement accurately describes the difference between Cushing's Syndrome and Addison's Disease?

A.Cushing's has high cortisol; Addison's has low cortisol.
B.Cushing's has low cortisol; Addison's has high cortisol.
C.Both have normal cortisol levels.
D.Both are caused by adrenal tumors.

35. What is the purpose of the ACTH stimulation test in diagnosing adrenal insufficiency?

A.To measure cortisol levels
B.To differentiate primary from secondary adrenal insufficiency
C.To assess electrolyte balance
D.To evaluate blood pressure

36. Which symptom is NOT associated with Cushing's syndrome?

A.Easy bruising
B.Weight gain
C.Hypotension
D.Moon face

37. What is the key concern for patients suffering from Cushing's Syndrome?

A.Increased risk of cardiovascular disease
B.Decreased risk of infections
C.Low blood pressure
D.Rapid weight loss

38. True or False: Stress increases cortisol production in patients with Addison's Disease.

A.True
B.False
C.Only with treatment
D.Depends on the individual

39. What type of replacement therapy is required for Addison's disease?

A.Mineralocorticoids only
B.Glucocorticoids and mineralocorticoids
C.Only dietary adjustments
D.Surgical intervention

40. Which medication is commonly used to manage Cushing's Syndrome?

A.Ketoconazole
B.Metformin
C.Levothyroxine
D.Amlodipine

41. Which of the following is NOT a symptom of Addison's Disease?

A.Nausea
B.Weight loss
C.Severe headaches
D.Fatigue

42. Which of the following skin changes is typical for Cushing's syndrome?

A.Hyperpigmentation
B.Purple striae
C.Thickening of skin
D.Dry skin

43. What lifestyle change should be encouraged for a patient with Cushing's Syndrome?

A.Regular exercise and balanced diet
B.Increased caloric intake
C.High-sugar diet
D.Sedentary lifestyle

44. What is a key aspect of long-term treatment for Addison's Disease?

A.Short-term steroid use
B.Intermittent fasting
C.Lifelong glucocorticoid and mineralocorticoid replacement
D.Increasing exercise levels

45. In terms of treatment, what is often the first step for Cushing's syndrome?

A.Glucocorticoid replacement
B.Medication to suppress cortisol
C.Surgery to remove tumors
D.Radiation therapy

46. Which of the following lab results would most likely indicate a diagnosis of Cushing's Syndrome?

A.Elevated cortisol levels
B.Decreased glucose levels
C.Low sodium levels
D.Increased potassium levels

47. What should patients with Addison's Disease carry for emergencies?

A.Short-acting insulin
B.Emergency hydrocortisone injection kit
C.Glucose tablets
D.Antihypertensive medication

48. Which adrenal condition is characterized by both weight loss and low blood pressure?

A.Cushing's syndrome
B.Addison's disease
C.Hyperaldosteronism
D.Pheochromocytoma

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