Epidemiology cohort vs case-control studies exam review
This flashcard set reviews key concepts and terminology related to epidemiology cohort and case-control studies, focusing on their definitions, differences, advantages, and disadvantages.
Quiz(24 questions)
1. What is the primary objective of a cohort study?
Terms in this Study Set(24)
Flashcards 1(12)
Cohort study definition?
A research design that follows a group (cohort) over time to assess outcomes.
Case-control study process?
Starts with outcomes, identifies cases, then compares to controls.
True or False: Cohort studies are always retrospective.
False. Cohort studies can be prospective or retrospective.
Fill in the blank: In a cohort study, ____ are followed over time.
participants
Comparison: Cohort vs Case-Control studies.
Cohort studies: follow subjects forward. Case-control: look backward at exposures.
Advantages of cohort studies?
- Can establish time sequence - Observe multiple outcomes - Less recall bias
Disadvantages of case-control studies?
- Recall bias - Cannot determine incidence - Requires clear case definitions
When to use a case-control study?
Use when outcomes are rare or when studying multiple exposures.
What is a risk ratio?
Risk ratio (RR) compares the probability of an outcome in two groups: RR = .
Example of a cohort study?
Study smokers vs non-smokers over 10 years for lung cancer incidence.
Purpose of matching in case-control studies?
To control for confounding variables by ensuring cases and controls are similar.
True or False: Case-control studies provide direct measures of incidence.
False. They estimate associations, not direct incidence rates.
Flashcards 2(12)
Cohort study advantages?
1. Can establish incidence. 2. Follows over time. 3. Less recall bias.
Case-control studies: strengths?
1. Quick and cost-effective. 2. Good for rare diseases. 3. Requires fewer subjects.
True or False: Cohort studies are always prospective.
False: They can be prospective or retrospective.
Fill in the blank: In a case-control study, we start with ____ and look for exposure.
cases (disease status)
Cohort vs Case-control: main difference?
Cohort studies start with exposure; case-control starts with disease.
Cause → Effect: Cohort study example?
Smoking (cause) → Lung cancer (effect) assessed over time.
What is a major bias in case-control studies?
Recall bias: participants may not accurately remember past exposures.
Define 'confounding variable'.
A variable that influences both the exposure and outcome, potentially skewing results.
What statistical measure compares odds in case-control studies?
Odds Ratio (OR): compares odds of exposure in cases vs controls.
True or False: Cohort studies can assess multiple outcomes.
True: They can evaluate various health outcomes related to the exposure.
Case-control studies use which sampling method?
They often use 'matching' to pair cases with controls based on characteristics.
What is a limitation of cohort studies?
They require large sample sizes and long follow-up periods, increasing costs.
Questions in this Study Set(24)
1. What is the primary objective of a cohort study?
2. Which of the following is an advantage of cohort studies?
3. What characterizes a case-control study?
4. What is a primary benefit of case-control studies?
5. True or False: Cohort studies are typically less expensive than case-control studies.
6. True or False: Cohort studies can only be prospective.
7. In a cohort study, what is typically measured over time?
8. In a case-control study, researchers look for exposure among which group?
9. Which of the following statements is true about cohort studies?
10. What distinguishes cohort studies from case-control studies?
11. What is a limitation of case-control studies?
12. Which scenario illustrates a cause-and-effect relationship in a cohort study?
13. When might a researcher choose to conduct a case-control study?
14. What is a common bias associated with case-control studies?
15. What does the risk ratio (RR) represent?
16. Define 'confounding variable'.
17. Which scenario best illustrates the cohort study design?
18. Which statistical measure is commonly used in case-control studies?
19. What is the main purpose of matching in case-control studies?
20. True or False: Cohort studies can only study one outcome at a time.
21. True or False: Case-control studies can provide direct measures of incidence rates.
22. What sampling method is commonly used in case-control studies?
23. Which study design is best suited for investigating rare diseases?
24. What is a limitation of cohort studies?
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